Towards a Cure – T2D35

//Towards a Cure – T2D35

Protective Responses

Over 50% of American adults are estimated to have prediabetes or diabetes. The twin cycles (hepatic and pancreatic) are not simply rare metabolic mistakes leading to disease. These responses are almost universal because they serve as protective mechanisms.

Protective? I can almost hear you gasp. Insulin resistance and beta cell dysfunction are protective? Yes. Absolutely. What do they protect us from? The very name gives use the vital clue. Insulin resistance protects the liver from too much insulin. Our body is resisting the excessive insulin, which is harmful.

Imagine the liver as a balloon that can be filled with sugar and fat, the two storage forms of food energy. Normally, when we eat, insulin goes up, storing some of this food energy. When we stop eating, during fasting, insulin levels fall, releasing some of the stored energy for the rest of the body.

When insulin levels stay elevated for a prolonged period, the liver fills up with sugar and fat, like an over-inflated balloon. The pressure inside the liver goes up and up, making it increasingly difficult to move sugar into this overfilled liver. This is insulin resistance. The liver simply cannot store any, so rejects the incoming sugars, becoming resistant to insulin’s normal signal. Glucose piles up outside the cell in the blood.

This provokes a compensatory hyperinsulinemia. Like trying to inflate the over-inflated balloon, it works for a time. However, it becomes more and more difficult. Ultimately, the liver was only trying to protect itself from the damaging effects of the high insulin. The problem is not the insulin resistance, but original hyperinsulinemia.

The liver is busy trying to clear the fatty congestion by exporting this new fat. Some of it accumulates in the pancreas, eventually clogging it and lowering insulin levels. This is exactly the correct protective response. Since high insulin is the very problem that causes type 2 diabetes, reducing insulin is the most effective protective strategy.

Blood glucose surges to abnormally high levels and spills out into the urine causing many of the symptoms of frequent urination and thirst. This too can be understood as an appropriate, protective mechanism. Forcing more glucose into the over-filled liver and pancreas will eventually destroy it. The body is now trying rid itself of the toxic glucose by eliminating it through the urine.

Obesity, too can be understood as a protective response against excessive de novo lipogenesis. Adipocytes are specialized cells that store fat (triglycerides) without problem. Without fat cells to store this newly created fat, it would otherwise immediately deposit in the organs and cause type 2 diabetes. In the rare genetic disease of the Beradinelli-Siep lipodystrophy‏ syndrome there is a congenital lack of fat cells. Virtually all of these patients develop type 2 diabetes, often by their teenage years, as excess fat from both diet and de novo lipogenesis deposit directly in the liver and muscles.

Long standing fatty liver causes scarring and will soon become the leading cause of liver failure in North America. Long-standing fatty pancreas will eventually lead to scarring as well, and after many decades, the pancreas is destroyed. To protect itself, the body needs to rid itself of this excessive toxic glucose load. By forcing the glucose out into the blood, it will spill out in the urine. This causes many of the symptoms of excessive urination and weight loss, but at least the toxic glucose load is being excreted.

Implications

This new understanding carries several important implications. First, type 2 diabetes results from a single underlying, unified mechanism. It does not result from two entirely separate pathophysiologic mechanisms, one for insulin resistance and another for beta cell dysfunction. The natural history and all of the manifestations of type 2 diabetes can be explained from excessive fatty organ infiltration.

Too much de novo lipogenesis results in fatty liver and insulin resistance. Too much fat in the beta cells results in lower insulin production. But hyperinsulinemia is ultimately the root cause of the entire problem.

Secondly, both defects of insulin resistance and the beta cell dysfunction are entirely reversible by removal of the excess fat clogging the organs. Contrary to popular belief, the pancreas is not scarred and burnt out beyond repair. Instead, the pancreas is simply clogged with fat. Once you unclog the fat, the pancreas starts to work again and insulin is secreted normally.

Thirdly, and perhaps most importantly, type 2 diabetes is both preventable and reversible, not chronic and progressive. It is not a life sentence. This new dawn carries tremendous hope for those afflicted. We only need to understand the underlying disease and apply our new knowledge. Our treatments were ineffective, and so we believed progression was part of the natural history the disease itself. Instead, the culprit was our fundamental misinterpretation of this disease.

Towards a Cure

In any disease, success depends upon identifying and treating the underlying cause, not the symptoms. For example, a bacterial infection may cause symptoms such as fever. The root cause is the bacterium and fever is only a symptom. To cure the disease, you must address the root cause, in this case, an antibiotic to kill the bacteria. This also successfully eliminates the symptom of fever.

But if you simply treat the symptom, there is no benefit. In this case, you can treat the fever with acetaminophen, but the infection persists unabated and may eventually kill you. Once you stop taking acetaminophen, the fever returns because the disease has not been treated. This may seem like the disease is chronic and progressive, but only because the treatment is incorrect. Treating the fever is only symptomatic treatment, since the fever is not the actual disease.

The exact same problem exists in type 2 diabetes. The root cause is hyperinsulinemia, and the symptom is high blood glucose. Type 2 diabetes, and indeed all the manifestations of the metabolic syndrome are diseases caused by too much insulin. Yet our current treatment paradigm focuses on lowering the blood glucose, which is only the symptom of the disease, but not the disease itself. Instead of treating the hyperinsulinemia, we were treating the high blood glucose.

The currently recommended treatments for type 2 diabetes include insulin, oral hypoglycemic drugs and low fat diets. Fifty years of experience tells us that these treatments do not cure the disease and only treat the symptoms. All these therapies are directed towards lowering blood sugar, but not the underlying hyperinsulinemia. In fact, all of these treatments raise insulin.

The treatments that are known to lead to a cure – fasting, bariatric surgery and low carbohydrate diets all share one feature in common. They are all treatments that lower insulin. Here’s comes the sudden, horrifying realization. The treatments we have been using for type 2 diabetes were EXACTLY wrong. Too much insulin causes this disease. Giving insulin or drugs that raise insulin will not make the disease better. It will only make it worse!

It is no different from treating alcoholism with more alcohol. Treating alcohol withdrawal by giving more alcohol will certainly improve symptoms in the short-term. But the disease, the alcoholism will get worse.

This is precisely what happened. Type 2 diabetic patients are generally started on one medication at diagnosis. This only treats the symptoms, so over time the disease gets worse, and the dose is increased. Once the maximum dose is reached, a second, then a third drug is added. After that, insulin is prescribed in ever increasing doses in a desperate bid to control the blood sugar. But, if you require higher and higher doses of medications, your diabetes is not getter better, it is getting worse. The treatment was exactly wrong.

In type 2 diabetes insulin levels are high, not low. Injecting more insulin is not going to help treat it. Yes, in the short-term, the symptom of high blood sugar is better, but the disease, the diabetes was continually getting worse. How did we expect that giving more insulin to a patient with too much already would help? Our standard accepted treatments were precisely how NOT to treat type 2 diabetes.

 

2017-10-12T21:33:14+00:00 66 Comments

About the Author:

Dr. Fung is a Toronto based kidney specialist, having graduated from the University of Toronto and finishing his medical specialty at the University of California, Los Angeles in 2001. He is the author of the bestsellers ‘The Obesity Code’ and ‘The Complete Guide to Fasting’. He has pioneered the use of therapeutic fasting for weight loss and type 2 diabetes reversal in his IDM clinic.

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66 Comments on "Towards a Cure – T2D35"

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Jane
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With a low carb, full fat diet, I have succeeded in coming off Gliclazide before Christmas and off slow release Lantus insulin a few weeks ago. I am still on Metformin. I am due to have my Hba1c test in a couple of weeks, but daily my bs levels have been volatile since coming off insulin from 5.6 to 9.1 whilst always sticking to the same diet. Is there any chance of my ever coming off Metformin if I continue with this way of eating and how can I aid this? I do sometimes do an 18:6 fast but have… Read more »
Roger Bird
Guest
Dear Jane, I presume that you are European by your numbers of your blood sugar. If you want Americans to understand it, multiply by 18, so your 5.6 to 9.1 becomes 100.8 to 163.8. Yikes! That is high. I strongly recommend that you push harder on the fasting. I just did a 7 day fast with one zero calorie (or close to it) green smoothie once a day. It was the best 1 week improvement by all markers that I have ever had, especially disposition. The longer the fast, the deeper it works. I still have 20 lbs. to go,… Read more »
nathalie
Guest

What is your recipe for your zero calorie green smoothie?

Lindamusician
Guest

Roger Bird, your comment is very interesting. I would also like to know how to make your “almost 0 calorie” green smoothie, if you would be willing to share. Thanks.

Kok-Hong Wong
Guest

Sounds like you are making good progress.

There is no rush as this is a marathon, not a sprint. Our body needs time to heal itself from the years of “nutrients” overload.

That said, I found that 18:6 fast works best when I do it over 2 consecutive days and skipping dinner instead of breakfast. That helped to lower my fasting glucose to 5.5 mmols/L (100mg/dl). Coincidentally my HbA1c had also stabilized at 5.5% from 11% and have maintained it since Dec 2015.

VLC.MD
Guest

I wouldn’t even worry about Metformin. It improves insulin resistance and is the only diabetes medication to show *INCREASED* longevity. I’m not sure how much Metformin increases insulin … I’ll say it increases insulin the least out of any other diabetes medication that lowers A1c.

Dr.rob
Guest

The entire field of Type2 diabetes industry is wrong and immoral. It generates massive amount of money treating the symptom – high blood glucose. There is no money in treating the actual disease – hyperinsulinemia. They will fight hard to preserve status quo.

But because of doctors like Dr. Fung people will know the truth and start demanding answers from organisations like ADA. Will they admit, that they were not helping and even harming patients? Maybe governments should step in?

Any way, big thanks to Dr. Fung for another great post!

Joe
Guest

The government did step in and helped cause this diabetes epidemic by telling everyone “fat is the villian” and subsidizing farmers who produce corn, wheat, and soy to make those foods really cheap.

GraceInYourFace
Guest

The truth is never widely accepted and promoted but by a few, therefore even if there is a cure to type 2 diabetes (which I believe this is) it will not be widely accepted. Of course only my opinion and I do hope I am wrong.

JR62
Guest

Organisations like ADA are Big Pharma funded. They will never admit anything. Step away from those.

glib
Guest

But, let us face it, the cardiovascular disease and cancer industries are even worse. We live in a very corrupt society.

Lori
Guest
Dr.rob We were just talking about that yesterday. Imagine if all obstetricians told their patients to have 2 drinks a day because it was good for the fetus or eat raw meat because it builds up the fetuses immunity! They would be sued from here to tomorrow. The problem is the standard of care for T2D and CAD is a low fat diet, whole grains and 60 grams of carbs per meal. You follow the standard of care, you are not liable even if there is a bad outcome, you deviate and even if your patient dies or is injured… Read more »
steve
Guest

I like this and wonder the same thing
(If insulin is the cause, then why not create a pill that reduces insulin instead of increasing it?)

bill
Guest

Because that would be bassackward. Why would you want to
eat CRaP and then take a pill? Lowering insulin will just cause
your body to leave glucose in the blood. Why not just eat the
foods that don’t give you high blood glucose?

Lori
Guest
Not everyone can or wants to. There is already a medicine that causes excess sugar to depart through the urine. Combine that with lowering insulin and you have something. According to what I have read, it is the insulin resistance that happens first not the high blood glucose. Not every obese person is diabetic. They eat plenty of CRaP and are ok. Why shouldn’t diabetics? If someone is diabetic WHY do they have to give up Pizza forever? Whether they do LCHF or Ornish they still have to give it up. Sorry but what passes for pizza in LCHF world… Read more »
Brigitte
Guest
Lori, insulin resistance does not just happen. It is the result of chronically elevated blood insulin levels which are the results of chronically elevated blood sugar levels, usually from eating too many carbs at any one sitting or eating carbs too frequently. Insulin levels, insulin resistance and blood sugar are some of the larger cogwheels in a complex metabolic clockwork. The easiest way to stop this clockwork moving ever forward is not replacing one wheel with a different sized one that stops a wheel spinning but moves two or three other hitherto static ones and therefore causing unplanned movements. The… Read more »
JR62
Guest

Some people can stand more Crap than others. If one settles for that, one will survive until old. The others won’t. Maybe that is the whole meaning. In The New Brave World all peasants will eat Monsanto’s owned grains and will be relative healthy. Only the rich ones can have animal foods.

Lori
Guest
Brigitte While I agree with you for myself, the reality is many do not do as they please, instead their doctor tells them eat 60 grams of carbs at each meal and they do and keep getting sicker and are told that T2 is progressive and unstoppable and that is why. NOT the CRaP they are eating. How is that a choice? Many people I know do not have the capacity to research. To be honest, while LCHF and IF have really been working well for me for about 2 months, there is a part of me that wonders if… Read more »
VLC.MD
Guest

Removing Insulin causes this little thing we doctors call Ketoacidosis. https://www.youtube.com/watch?v=lgqsIL29YOQ Nasty stuff. But Bill, I love your creative thinking. 🙂

Marlese Wacek
Guest

Keep up the great work and continue spreading the word on how to cure type-2 diabetes and insulin resistance.

Srinath
Guest
There is no money in fasting. I did low carb, then accidentally fasted and then I started fasting. Completely getting rid of all problems, including high BP and inflammation that I had surgery to treat. Yea, plantar fasciitis in right foot I had surgery to treat and still used to have mild pain. Left was pretty bad too, and 2 days into a fast, it all disappears. Too bad it comes back even with very low carbs. Anyway, 90% of physical problems are likely due to hyperinsulenimia. Fasting will cure it. That will make pharmaceutical and food companies broke. Simple.… Read more »
Joe
Guest

Once again you have explained so it can be understood. That is what I truly like about your blog you write so those of us without medical degrees can get it. I appreciate your blog and look forward to each installment to keep me chugging along to the best health of my life so far. Have a ways to go but I can see the light. Thank You!

Dr. Adrian
Guest
I also wonder if the rise in eating disorders generally has been in part due to the change over to low-fat. I worried at first very much about how people with eating disorders would respond to this diet, and especially to fasting (obviously most people’s disordered eating goes in the direction of overeating or overeating and purging, and I have long believed anorexia to be a physiological response to foods the body “simply does not want to consume”) I believe firmly now after some months of resisting the idea (often quite angrily!), that if the stage is set correctly, the… Read more »
Bob
Guest
Amen, This Blog posted here today should be a mandatory read for to every medical provider and every medical student. If they want more information/proof they can read his books and previous blogs and see Dr Fung’s logic behind this issue. I am amazed how he writes in such practical terms so the laymen can understand, that is a gift. I feel fortunate to have run across his name and have purchased and read every book and blog he has written. I myself are in the Pharmacy field and see how far off we are treating Type-II diabetes. But big… Read more »
Walt
Guest
Bob, I think that is kind of conspiratorial. As Dr Taylor stated when asked essentially the same question, it will take until Medical Schools update their text books as the ones they use now predate the work Dr Taylor and others have done proving T2D is reversible/curable. Doctors, pretty much are bound to practice medicine as they were taught. Dr Fung explained this as it related to his early days practicing medicine. He concluded what he was doing clearly was not working. By not effervescently praising Dr Fung over the work of Dr Taylor and others, in no way detracts… Read more »
steve
Guest

So is this like alcoholics in the sense they can never ever again take a drink of alcohol. Are we to stay Keto forever and never ever again taste a twinkie☺

Apicio
Guest

Yes. You will not heal by going back to what broke you.

Walt
Guest
I am not a dr but I do not believe that is true, one must stay on a keto diet. I believe individuals have a capacity to tolerate carbohydrates. If you blew past your tolerance long enough to acquire T2D, which takes over a decade, yes you will become diabetic again. As Dr Taylor explains in “Reversing the Irreversible”, individuals have a set point of BMI, in all of his clinical trials once the individual drops below their BMI set point their T2D disappears as the pancreas and liver resume normal function. So long as one stays below their BMI… Read more »
Walt
Guest

And that was well over a year ago and my A1C has stayed mid 5’s. I am trying to do keto and IDF now to get A1C to mid 4’s and BMI to 20. That should, in theory, give me far more dietary latitude for occasional excursions into ‘treats’. But I don’t want to eat like a bird for the rest of my life.

Goose
Guest

Nice weight loss Walt!

My BMI was 25 at its highest twenty years ago, and I was a mess. Now @ 22 and my body is humming along with a LCHF/lazy keto approach. Maybe your A1C will normalize somewhere below 25 and you won’t have to get to 20, which as you know is quite low.

Re eating like a bird, do you visit r/keto on reddit? There are lots of recipes and good conversations there on how to fit in treats while staying in ketosis.

Jillm
Guest

I treat myself often, but not with food.

glib
Guest

no, after you heal you will be able to eat relatively high carb, high fiber foods. I eat potatoes, carrots and beets in abundance, a lot of natto, and some beans and squash. The high fiber keeps the GI low, but additions such as apple cider vinegar in a root salad, or sauerkrauts of all sorts, will further lower the GI (Dr Fung himself states this often). Today I have chickpeas with a preserved lemon ground, and preserved olives and mixed in for lunch. Still no grains and sugar.

Walt
Guest
I still think the use of ‘reversal’ as in Dr Taylor’s “Reversing the Irreversable” or as Dr Fung uses it above, and the use of “towards a cure” detracts from the notion of “CURE”. In other words either it is or it isn’t. As my ex doctor told me “good, you’re managing it with diet and exercise”. No, I believe I’ve cured it, much like an STD, it was treated and now it’s gone”. As weird as that analogy is, it’s valid as curing an STD doesn’t mean it can’t be re-acquired. But that is distinctly different than saying it’s… Read more »
BobM
Guest
I wonder if there are phases the liver and pancreas go through during a process of losing weight, being on low carb, and fasting? I had my insulin tested in June of 2015. It was 3.8 uIU/mL. This was a “normal” 12 hour fast. I then had my insulin tested again in September 2015, after 4.5 days of fasting (blood test Friday morning, had not eaten since Sunday evening), and it was <3.0 uIU/mL. That was lower than the test could go. I had another 12 hour fasting test taken in October of 2016. My insulin was 33.0 uIU/mL, and… Read more »
Gloria
Guest
Doctor Fung, thank you again for another highly instructive and informative article. I am convinced that after eating a low-fat high cabs diet for 25 years I worked my way toward pre-diabetes (A1C 5.9/fasting glucose 112), and things were not getting any better. I was increasingly frustrated by my inability to control my weight even while being active. Several years ago, I trained and ran a half marathon. Training took me around 5 months, especially since I had never run long distances. I remember trying to eat “healthy whole grains” and other carbs to ensure I had enough energy to… Read more »
NicoleS
Guest
Gloria – your story is so similar to mine! After my second child, I started working out hard and lost some of the baby weight although I never got down to my pre-pregnancy weight from my first child. I was also breastfeeding a lot but I still had the pooch! Doctors told me it was because of breastfeeding and once I stopped, the weight would melt off. But when I stopped, the weight just piled on! It made no sense to me! I was doing obstacle races, lifting weights and running and while I was extremely fit, the weight kept… Read more »
Stephen T
Guest

Excellent result, Nicole. Well done.

What a pity people get so much bad advice before finally finding something that works.

Ron Hunter
Guest

Dr. Fung – here’s my challenge to you. Joseph Kraft’s radio assay / extended glucose tolerance test needs to become a standard test. It boggles my mind this is not being done more to cut off cases of diabetes before they manifest themselves.

Walt
Guest

Ron, a glucose tolerance test IS a standard test. It is just far more expensive than FBG, which is why they give it instead. Likely insurance companies won’t pay for it. However, if you tell your dr you want it, you can get it just you’ll be paying for it from the tester facility.

Ron Hunter
Guest

Kraft does a glucose tolerance with a radioactive assay of insulin levels. He also does a 5 hour test. It gives him an insulin response curve for a person. The insulin assay can identify people who are actually diabetic but have normal fasting blood sugar and A1C’s.

Joe
Guest

Dr Fung has got it all wrong, according to this video! Hard to believe there are MD’s out their spewing this garbage and propagating the falsehoods…

https://www.youtube.com/watch?v=1cl2IX94GCI

Dr. Adrian
Guest

Joe, Dr. McDougall is one of the worst snake-oil salesmen out there (unless what you meant was ironic and the garbage coming from McD, hard to tell on a message board!). My view, if you want to get an eating disorder right this minute, follow Fuhrman or McDougall. Should do the trick.

Joe
Guest

The garbage is coming from a medical doctor telling people sugar helps diabetics.

Lori
Guest

There are studies that support it. The Duke Rice Diet claimed to cure diabetes with rice.

Here is an interesting perspective that puts it into context

https://deniseminger.com/2015/10/06/in-defense-of-low-fat-a-call-for-some-evolution-of-thought-part-1/

Adrian
Guest

Joe, full agreement, sorry I read that one wrong.

Dr.rob
Guest

Yes, it’s really hard to believe, that there are such a scientific illiterates, like Dr McDougall, that are driven more by ideology, than by what’s really happening.

Stevo74
Guest

Hi Dr. Fung,

Thank you for another interesting post. While reviewing an article on atrial fibrillation (see link below), I noticed the quote below in the conclusions. Infiltration of fat in the heart may also be a contributing factor for atrial fibrillation.

You may have stumbled upon a mechanism for a much large scope of obesity related diseases than you originally thought.

Keep up the great work.

https://www.ncbi.nlm.nih.gov/pubmed/26139051

“…Obesity was associated with reduced posterior LA endocardial voltage and infiltration of contiguous posterior LA muscle by epicardial fat, representing a unique substrate for AF.”

SamB
Guest
I was able to get off my metformin after two weeks, eating low carb, high fat. I’m drinking bulletproof coffee each morning, and I’m having some stomach issues. I’m thinking, since I’m not use to coffee, that this may be affecting my stomach, so I’m going to lay off the coffee for a few days to see if that is the cause. Coffee is acidic, so that brings me to another concern. I’ve been told for years that dairy products are extremely “acidic”, so that makes me wonder if I’m becoming too acidic. I’ve been a vegetarian for 37 years,… Read more »
Ron Hunter
Guest

Coffee is pretty bad on the stomach and is one of the items that is recommended that people with reflux avoid. Two things I greatly enjoy, coffee and wine both do no favors to my reflux problem.

Adrian
Guest
Ron, please forgive the unsolicited advice, but I have had great relief also (my reflux was treated several times with upper endocsopy dilation, so I don’t know that things will ever fully heal even with best diet) is the MedSlant pillow (pricey but cheapest on Amazon). It folds in half, has very comfortable ridges as opposed to solid foam, and I manage to stay on it most of the night. Coffee I limit to one 6 oz cup in the a.m. with some coconut oil, and the other 2 ounces as iced coffee with lunch. Very infrequently enjoy a small… Read more »
Ron Hunter
Guest

Thanks so much. Someone else told me about slant pillows. Right now I just sleep on multiple pillows. I’ll check it out.

KidPsych
Guest
SamB
Guest

Thank you!

Vero
Guest

Does dry red wine cause insulin to rise?

Walt
Guest

According to Dr Roy Taylor, wine is metabolized as fat as there is actually very little sugar in it, per unit volume. That is still a head scratcher for me. However, on the FastingTalk podcast with Jimmy Moore (coauthor of Complete Guide to Fasting, and Meghan Ramos, the director of IDM, wine is perfectly fine to consume on a fast. That said, even fat will raise insulin, though fat does it the least of the three mega-nutrients, carbs, protein, fat, in that order.

Denise
Guest

This t-shirt says everything.
http://amzn.to/2rKrLT4

Walt
Guest
Did people see the article in the NY Times from 5/03/2017? https://www.nytimes.com/2017/05/03/well/eat/fasting-offers-no-special-weight-loss-benefits.html?comments&_r=0#permid=22650370 This is their write up of the JAMA article http://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2623528 published May 1, 2017 Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese AdultsA Randomized Clinical Trial John F. Trepanowski, PhD1; Cynthia M. Kroeger, PhD1,2; Adrienne Barnosky, MD1; et al Key Points Question Is alternate-day fasting more effective for weight loss and weight maintenance compared with daily calorie restriction? Findings This randomized clinical trial included 100 metabolically healthy obese adults. Weight loss after 1 year in the alternate-day fasting group (6.0%) was… Read more »
Mags299
Guest
Hello Walt, How do you square this phrase from the write-up?: “Participants in the alternate-day fasting group ate more than prescribed on fast days, and less than prescribed on feast days, while those in the daily calorie restriction group generally met their prescribed energy goals.” To me that says (along with the 25% of energy needs on fast days, ironically not in quotes in the text) that they did not actually follow a fasting regime alternate-day or otherwise. Just a alternate-day calorie restriction. Now I am all for starting with the little 500 calories during a fast day as the… Read more »
Adrian
Guest

Mags299, that is really great. Thank you so much.

Walt
Guest
Mags299, I can’t square it. I also can’t get the full text without paying for it, which I am not inclined to do. The summary didn’t say ADF doesn’t work, just it doesn’t work any better. That, I actually believe as I lost 125lbs on the so-called CRaP diet and went from A1C or 8.5 to 5.5. The issue I have with Fung’s rhetoric is the denigration he shows for all things not in his story-line. Kevin Hall is a reearcher, endocrinologist, PhD, if not MD, and the best Dr Fung can do is “here’s $5.00 go buy yourself a… Read more »
Walt
Guest

Oh, in Dr Taylor’s protocol, virtually 100% cure rate. In subsequent trials expanding length of T2D vs cure rate, the longer one has lived with T2D the less likely it is for a complete cure, but there is a consistent, regardless of length of T2D everyone improved. The cure rate drops as T2D duration increases. There were a few that had T2D for 30yrs that reversed it, but not all of them.

Aaron
Guest

Hi Walt and Mags299,

I think the point missed in the study and the article, which Dr. fun points out somewhere, is that even though both groups regained their approximate weight back, they did so with increased muscle mass and decreased body fat percentages. This with the history of lower insulin production created a situation where they were healthier.

My wife has noted Dr. Fung’s sarcasm a few times to me also. i thank that both of you pointed out the other important factor, like not true fasting and what type of diet was returned to.

Walt
Guest

Aaron, I don’t recall seeing any Dr Fung comment at all. That study just wrapped up. Yes, they didn’t address several thing. They didn’t say ADF didn’t work, simply, by what they were measuring against, it didn’t work any better.

Walt
Guest

Mag299, ditto, congratulations. As the saying goes, how you get there is far less important than, that you got there! But, as they say, nothing succeeds like success!

Mary
Guest

Is there a good link somewhere for what the various numbers in a fasting serum insulin level test are considered good/normal/bad/terrible ? – I’ve seen reference to the difference between 2 uIU/mL and 8 uIU/mL being statistically significant in correlation with insulin related disease incidence, but the provider that administered my test recommends 17 uIU/mL as the “high” cut-off, and measured mine as 36 uIU/mL (with a fasting glucose level of 80 mg/dL, so in the considered normal level) – I don’t seem to be able to find anything that discusses a number that high!

Angela A Stanton, Ph.D.
Guest

Awesome explanation, as always! Very simple to understand and easy to visualize. It should help many people! Thanks for sharing your knowledge!
Angela

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